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Fatal Car Accident on Interstate 64 in Frontenac, MO, on November 04, 2026

Fatal wrong-way crash involved three cars near North Ballas Road

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Published:
Last Updated:

St. Louis, MO

 (

Nov 04, 2026

) - 

Two drivers died in a three-car wrong-way crash on Interstate 64 in Frontenac, Missouri, on November 4, 2026. The collision occurred around 9:30 p.m. in the westbound lanes east of North Ballas Road. The third driver was uninjured, and all westbound lanes were temporarily closed for several hours.
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Three cars were involved in a fatal wrong-way collision on Interstate 64 in Frontenac, Missouri, on Wednesday night, November 4, 2026. The crash took place around 9:30 p.m. in the westbound lanes, east of North Ballas Road.

A crash report from the Missouri State Highway Patrol described the initial collision as head-on. A 25-year-old woman driving a midsize car was traveling in the wrong direction in the westbound lanes when her vehicle struck a luxury car driven by a 30-year-old man.

After that collision, a third car struck the rear of the man's car. The driver of the third car was not injured, according to the report.

Paramedics pronounced both the woman and the man dead at the scene. Their names were not supplied in the available crash information.

Road crews temporarily closed all westbound lanes of Interstate 64 for several hours as they cleared the scene of the three-vehicle crash.

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Accident Victims:
Accident Victim
Name:
Age:
25
Injury:
Fatal
Accident Victim
Name:
Age:
30
Injury:
Fatal
Accident Details:
Location:
St. Louis, MO
Type:
Car Accident
Severity:
Fatal
Collision:
Head On, Rear End, Multi-Vehicle
Issues:
Wrong Way
Interstate:
Interstate 64
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