Fatal Multi-Vehicle Crash on Interstate 70 Near Exit 125, Missouri, November 04, 2026

A 57-year-old Columbia man died after a multi-vehicle crash on Interstate 70 near Exit 125 in Missouri on Wednesday, November 4, 2026. The collision occurred at about 10:40 a.m. and blocked traffic in the eastbound lanes, according to authorities.

The driver initially suffered serious injuries and was transported to a local hospital. The Columbia Police Department said he died from those injuries at about 9:25 p.m. that evening.

Another driver, identified as a juvenile, was also transported to a local hospital for minor injuries. No additional information about that driver was released.

The agencies gave different accounts of the number of vehicles involved. Columbia police reported that as many as five vehicles were involved. An earlier account from the Missouri Department of Transportation described a three-vehicle crash.

Columbia Fire Department crews encountered two vehicles showing damage ranging from moderate to heavy during their initial response.

One of the vehicles involved was carrying a Budweiser Clydesdale. Anheuser-Busch confirmed that one of its vehicles had been involved in the traffic accident and said both the driver and the horse were uninjured.

Assistant Fire Chief Zachary Grace described a crash involving a Clydesdale as a rare occurrence.

The available accounts did not describe how the crash began or specify when the eastbound lanes reopened to traffic.